Bosses at Great Western Hospital in Swindon say they will do all they can to keep disruption to services to a minimum during the severe weather conditions.
The hospital trust also runs the community hospitals in Chippenham, Trowbridge, Devizes, Savernake, Melksham and Warminster.
A GWH spokesman said patients with appointments and operations scheduled for tomorrow (Friday) should, if they can travel in safely, attend as normal unless the hospital contacts them.
The spokesman said contingency plans were in place to help essential staff get to the hospitals by using four-wheel drive transport.
The spokesman said it was too early to say if services will be affected but will be putting updates on its website – www.gwh.nhs.uk and Twitter - @GWH_NHS.