Jewellery, bags and an iPad were taken after thieves scaled scaffolding to gain access to a property in Warminster earlier this week.
Officers are appealing for witnesses and information after entry was gained to the home in Vicarage Road between 9.15am and 7.15pm on Tuesday.
Police are keen to hear from people who saw anyone on the scaffolding that day who would have not been using ladders or who looked out of place.
Anyone with information is asked to contact either DC Nick Holt or the Warminster Neighbourhood Policing Team (NPT) on 101 quoting crime reference number 54140025777.
Alternatively contact Crimestoppers on 0800 555 111.